If you are among those experiencing premature aging, then the gene responsible for embryo development may be blamed for!– or that your body is losing stem cells slowly!
Yeah, you got it right – I’m pointing right at the ATR gene. No, it’s not the presence of the ATR gene, but its absence may lead to such health crisis – at least what is found to occur in adult mice.
According to a study conducted by a research team at Abramson Family Cancer Research Institute of the University of Pennsylvania, the ATR gene helps body to respond to damaged DNA. And, this DNA damage response may lead to protein-mutations underlying certain cancer types and other disorders in humans.
In their experiment, the researchers found that the mouse cells — without ATR – are experiencing an overwhelming amount of DNA damage, lowering their capability to contribute to tissue renewal.
Although, 10 to 20 percent of the cells that escaped ATR deletion were found to be able to reconstitute tissues initially, in the long run — it appeared — these cells proved insufficient in maintaining tissue integrity!
So, can premature aging be considered a slow loss of stem cells, a deterioration stem cell reservoir? Perhaps, Eric J. Brown, a team researcher would agree to it, cuing from the recent finding.
